WHO WE ARE
Prilenia is a clinical stage biotech company, led by Michael Hayden, MD, PhD., together with a highly experienced team with a track record of success.
Michael is a world-renowned scientist in Huntington Disease research. He is the former President of Global R&D and Chief Scientific Officer at Teva Pharmaceuticals, where he led the development of ~35 new products towards approval in several major markets, predominantly in CNS.
The company has recently raised $62.5M in a Series A financing round to launch the planned HD and ALS late-stage clinical trials. The funding round was led by Forbion, and accompanied by Morningside Venture Investments, Sectoral Asset Management and Talisman Capital Partners. All of which are leading Venture Capital firms in the Life Science field.
Pridopidine, the company’s lead asset, is a highly selective sigma-1 receptor (S1R) agonist with an established safety profile and potential in multiple movement disorders and neurodegenerative diseases affecting adults and children.
Pridopidine has been shown to maintain functional capacity in early HD patients, as measured by Total Functional Capacity (TFC). Furthermore, it was recently selected from an international competition of over 30 potential therapeutics for inclusion in the first ever ALS platform trial, led by the Healey Center for ALS at Massachusetts General Hospital. The trials – Phase 3 trial in HD and the platform trial in ALS - are expected to commence in H2 2020 and in the face of compelling results could potentially lead to the registration of pridopidine for these indications.
In addition to the HD and ALS programs, Pridopidine is also being studied for the treatment of Parkinson’s Disease Levodopa Induced Dyskinesia (PD-LID) and other conditions.